Alzheimer's Disease

  Time is deceased was described for the first time in 1907 by the German psychiatrist Eloise as a timer.  In performing histopathologic studies of the brain of his patient Augustine suffering from dementia he brought to light the presence of 2 types of lesions in the brain.  Senile plaques and neurofibrillary tangles he reached the conclusion of a distinct disease of a cerebral cortex 100 years later, thanks to current scientific techniques research has made a great leap and the understanding of the disease.  We know that the brain is made up of neurons and that these are interconnected to form a vast network.  These connections known as synapses enable the transmission of information from one neuron to another.  And now it's time for us to cease 10 to 15 years before the appearance of the symptoms to main lesions forms in the brain.  Senile plaques composed of amyloid-beta protein and neurofibrillary tangles composed of tau protein.  How is the senile plaque formed?  On the surfa

 Hippocampus, which is known to encode a new protein called PGC-1α that acts as a strong synaptic activator in the hippocampus.  The fact of course remains there are many factors involved with stress and cognitive dysfunction including loss or disease of brain cells - but since we know this can happen more frequently then you might think people would assume it's related to the illness so doctors look for clues if they get an old wound on their scalp from being spanked/tossed around all day long?  Hippocampus in humans and other primates is associated with anxiety-like behavior. In addition to the hippocampal dysfunction that may be involved here, we are interested herein also in how impaired brain function relates directly or indirectly using a novel model of neurodegenerative diseases. We observed previously in Alzheimer's disease patients reduced cognitive performance on measures of attention span across two tests—the spatial working memory task and an executive function test

 With the growth of age, disease comes gradually and some of them become dominant. Family history and lifestyle are important.  This is a genetic condition that most often occurs after an accident or trauma to the head, especially when someone has died from this type of stroke. This can also happen if you are pregnant or suffering from traumatic damage such as your baby's birth.  The symptoms can include difficulty seeing, hearing, or thinking clearly, along with involuntary muscle spasms and mental confusion. 

  What is Alzheimer's disease?  Alzheimer's is a slow fatal disease of the brain affecting one in 10 people over the age of 65.  No one is immune.  The disease comes on gradually as abnormal protein fragments called plaques and tangles accumulate in the brain and kill brain cells.  They start here in the hippocampus the part of the brain where memories are the first to form.  Over many years' time, the plaques and tangles slowly destroy the hippocampus and it becomes harder and harder to form new memories.  Simple recollections from a few hours or days ago but the rest of us might take for granted are just not there.  After that more plaques and tangles spread into different regions of the brain.  Ellen cells and compromising function wherever they go this is spreading around is what causes the different stages of Alzheimer's.  From the hippocampus, the disease spreads here to the region of the brain where the language is processed when that happens it gets tougher and

 Neurodegenerative symptoms of ASD or other Neurodevelopmental disorders are associated with abnormal brain morphology. We first examined the pattern and location in which these abnormalities occurred based on a survey by Dr. David Risling, head of neurology at Boston Children's Hospital (BCCH) who conducted this study. Glucocerebellar neuropathy is thought to be caused by an enzyme deficiency in the nerve cells of your brain (glioblastoma multiforme). Glioblasts are a type 2 normal cellular organelle that grows over time from damaged or dying cell bodies. One gilded "glub" at the end helps with signal transmission among parts where it can affect memory formation, balance, movement coordination etc.: In this case, loss-of-function causes gliosis.

 Milder therapeutic drugs (such as riluzole) to help with nausea and vomiting. However, these medications have not yet been proven effective in treating this debilitating condition. A combination of several common antibiotics has shown success against severe cases but is rarely used for patients who do well on multiple classes," said Dr Richard Weisberg at University College London's Wellcome Trust Surgical Centre, where the research was carried out alongside Professor Nick Brown of Edinburgh University's School Of Hygiene & Tropical Medicine. The researchers tested 23 participants that had a history or present medical problem caused by chronic fatigue syndrome - one third were taking an antibiotic known collectively among clinicians as cephalosporins. In addition, treatment with intravenous corticosteroids was sometimes used in a subset of patients who presented a severely compromised immune status despite aggressive therapy for advanced cancer. The authors conclude t

 The effectiveness of these medications appears to be modest but significant for a large number of patients who can tolerate their side effects. On average, the cognitive enhancers slow down for six months or more the encroachment of Alzheimer's disease on multiple areas of functioning. "This study is important because it demonstrates that although milder therapeutic drugs (such as riluzole) have been shown in animal models and are currently being tested by doctors treating several different types Parkinsonian disorders, they don't eliminate both neurodegenerative symptoms and impairments in normal memory," says Dr Wollenbergs. He adds: I believe this paper will help us further understand how the medication works with cognition impairment.  So the drug is effective for a fixed time or months.